July 5, 2022


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Explaining Curcumin’s Health Benefits and Limitations

Curcumin is the main active ingredient in turmeric, which is native to Southeast Asia but is popular all over the world. Turmeric is most popular in India, where it is one of the main spices in curry powders. Its flavor is warm and bitter, and it has a striking yellow color.

Curcumin was first isolated by scientists around the turn of the 20th century, and in 1949, its antibacterial properties were first found. Subsequent research showed it to have anti-inflammatory properties, anti-oxidant properties, and several other marked benefits.

Health Benefits of Curcumin

Arthritis and Joint Pain
One of the most common uses for curcumin extract is combating the discomfort from joint pain and arthritis, including a limited range of motion, joint stiffness, excessive swelling, and lack of mobility. Research shows that curcumin inhibits many of the mediators of inflammation linked to rheumatoid arthritis, psoriatic arthritis, and osteoarthritis development.

Heart Disease
Curcumin may reverse steps in the heart disease process by improving the function of the lining of blood vessels. helping regulate blood pressure, blood clotting, and other factors vital to heart health. Also, researchers have found that curcumin can help reduce bad cholesterol (LD).

Weight Loss
Curcumin is also promising in being used as a weight-loss supplement, even for those who are struggling with metabolic disorders. Curcumin can decrease a cell’s efficiency to process nutrients, so it forces our bodies to burn fat to provide the energy it needs. It also helps weight loss by reducing insulin resistance, allowing cells to process more nutrients.

Alzheimer’s Disease
Many researchers have noted that India, where people’s diet consists of large amounts of turmeric, has a very low incidence of Alzheimer’s disease. In studies using curcumin on mice subjects, curcumin has shown memory improvement by protecting brain cells and decreasing the death of nerve cells.

Limitation of Curcumin

Despite being a powerful bioactive agent and natural antioxidant, curcumin is practically water-insoluble at ambient conditions of pressure and temperature, with many studies showing very low, or even undetectable, concentrations in blood and extraintestinal tissue. Major reasons postulated are due to its poor absorption, rapid metabolism, chemical instability, and rapid systemic elimination. Another major barrier to curcumin’s clinical efficacy is its poor bioavailability. Efforts have therefore been dedicated to developing curcumin formulations with greater bioavailability and systemic tissue distribution.

Among curcumin supplements on the market, Chenland CuminUP60® demonstrates high water solubility, and an increased cell uptake rate. It is 5x more bioavailable than other curcumins on the market. CuminUP60®™ is a premier natural ingredient made with Patent Pending CGSF technology. Usage of the Co-Grinding Solvent Free process provides an eco-friendly and sustainable solvent-free method to produce CuminUP60®™, incorporating high purity curcuminoids to significantly improve curcumin water solubility and bioavailability.

Cell culture study proves that CuminUP60®™ enters cells more easily than untreated curcumin. Comparatively, cells have a greater curcumin uptake when exposed to CuminUP60®™ at a rate twice the average curcumin products. Also, the water solubility test shows that CuminUP60®™ yields a concentration of 88.2 μg/ml, 53 times greater than other curcumin products on the market.